On 24 June 1981, the new building, complete with hangar, offices and sleeping quarters, was officially inaugurated. From then on, the Lausanne Rega base was on stand-by around the clock with its three teams, each comprising a pilot, paramedic and physician. The medical service was organised by Lausanne University Hospital (CHUV).

The operations carried out by the Lausanne base include road and sports accidents and inter-hospital transfer flights, as well as the transport of organs. The rescue helicopter flies to locations in the towns and the country, in the mountains and on and by the water.

Assisted by its partners, such as the police, fire brigade and other rescue services, the Lausanne base flies approx. 1,000 missions a year, around a third of which are, at least partly, carried out at night.